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faux saint laurent bag was founded with the intention of helping people worldwide discover their unique heritage TPPs written in English for any type of medical test were included (e.g. imaging, in vitro and in vivo medical tests). There were no restrictions in terms of publication date. All publication formats were included except for newsletters and PowerPoint presentations, as these did not report the methods in sufficient detail to review them.
Conducting cost-effectiveness analysis at early R&D stages of new tests can therefore help manufacturers to avoid significant investments in tests that do not have the potential to be cost-effective [65].
R&D:
Kern S. Why your new cancer biomarker may never work: recurrent patterns and remarkable diversity in biomarker failures. Cancer Res. 2012. https://doi.org/10.1158/0008-5472.CAN-12-3232.
Dittrich S, Tadesse B, Moussy F, Chua A, Zorzet A, Tangden T, et al. Target Product Profile for a diagnostic assay to differentiate between bacterial and non-bacterial infections to guide antimicrobials use in resource-limited settings: an expert consensus. Am J Trop Med Hyg. 2017. https://doi.org/10.1371/journal.pone.0161721.
WHO, FIND. Development of a Target Product Profile (TPP) and a framework for evaluation for a test for predicting progression from tubercolosis infection to active disease. 2017. https://apps.who.int/iris/bitstream/handle/10665/259176/WHO-HTM-TB-2017.18-eng.pdf;jsessionid=BD8E426CA555DE9FEAB589FF2A9B2CCC?sequence=1. Accessed 8 Nov 2018.
Robert Michael West
All authors contributed to the conception and design of the work. PC performed the search strategy; BS contributed to reference sifting whilst AAS conducted the data extraction. MM and RW solved any conflicts. PC, BS, MM and RW interpreted the data and drafted and revised the manuscript. The authors read and approved the final manuscript.
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